Tosoh Bioscience LLC is a major supplier of chromatography products to the pharmaceutical, biotechnology, and chemical industries. Our product line includes:TSKgel®, TOYOPEARL®, and Ca++Pure-HA® bulk media, TSKgel U/HPLC columns, process development products, dedicated systems for GPC analysis, and the LenS3™ MALS detector. We have optimal solutions for biological research, drug discovery, medicinal chemistry, agriculture, manufacturing, or other industrial applications.
Summary
Therapeutic proteins and nucleic acids, often referred to as biopharmaceuticals or biologics, are part of cell and gene therapy. These proteins have become immensely important in a treatment of various chronic diseases such as rheumatoid arthritis, cancer, and infectious diseases. The major objective of this co-op position (under close supervision of a scientist) is to develop and optimize methods for purification and analysis of biopharmaceuticals. Our current programs include method development for monoclonal antibodies (mAbs), oligonucleotides, and viral vectors (e.g. adeno-associated viruses) produced in various expression systems.
Reporting Relationships
- Reports to the Applications Group Manager.
Major Duties And Responsibilities
During the internship, the co-op student will learn the following laboratory and other skills:
- Perform protein purification activities in a team environment using a mixture of established protocols and perform novel biochemical and biophysical assays for the project as needed.
- Conduct experiments and provide data, analyze results, and prepare reports in a timeline driven process and contribute to the efficient operation of R&D laboratories.
- Exercise technical judgment in the design, execution, and interpretation of experiments, and use professional concepts to solve complex problems in creative and effective ways.
- Maintain a laboratory notebook and other technical documentation according to required guidelines.
- This is a laboratory-based position and, thus, anyone working in this environment, will comply with all required training, and maintain a focused attention on laboratory safety for themselves and a team.
- Maintain regular and reliable attendance.
- Uphold and adhere to the Tosoh Bioscience culture and guiding principles.
- Other duties as required.
Skills And Qualifications
- Basic knowledge of laboratory work, such as pipetting, buffer preparations, and use of standard laboratory instruments. Training will be provided.
- Basic understanding of chromatography theory and protein purification principles.
- Excellent writing skills to maintain laboratory notebook and to prepare technical reports.
- Highly motivated individual that can exhibit an attention to detail.
- Strong communication skills (written and verbal). Further training in presenting lab results in team and departmental meetings will be provided.
- Knowledge and experience with Microsoft Office software, as well as intermediate to advanced software skills with PowerPoint and Excel.
- Strong analytical and problem-solving skills, and able to think creatively.
- Able to learn quickly and work independently under general direction.
- Responsible for mature attitude, teamwork, and time management.
Physical Requirements
The physical demands of this job are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. Ability to sit and stand for extended periods of time. Ability to wear personal protection equipment (PPE provided) and work in the proximity of hazardous materials.
Tosoh Bioscience LLC is an Equal Opportunity Employer M/F/Disabled/Veterans
